SCHEMBL3396648

SCHEMBL3396648

O=C(/C=C\C(=O)OCc1ccccc1)OCCCO

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.68
LMNA P02545 1/20 0.59
AKR1B10 O60218 7/20 0.55
AKR1B1 P15121 7/20 0.55
CA12 O43570 2/20 0.55
CA4 P22748 2/20 0.55
CA6 P23280 2/20 0.55
CA5A P35218 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
TTR P02766 1/20 0.50
ALDH1A1 P00352 5/20 0.49
POLB P06746 1/20 0.49
MAOB P27338 1/20 0.48
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396658 1.00 HCAR2 (0.68) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL8416653 0.90 HCAR2 (0.72) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL8416661 0.90 HCAR2 (0.72) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL337504 0.86 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL357565 0.86 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL337503 0.86 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL3445677 0.86 HCAR2 (0.66) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL3445675 0.86 HCAR2 (0.66) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL27659194 0.84 HCAR2 (0.85) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL10732314 0.83 HCAR2 (0.72) HCAR2LMNAAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3114164-B1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES INC (US) 2025-07-02 EP disclosed
US-9976055-B2 Lower temperature cure coating compositions KING INDUSTRIES (US) 2018-05-22 US disclosed
EP-3114164-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS King Industries, Inc. (US) 2017-01-11 EP disclosed
US-20150197665-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 US disclosed
WO-2015106174-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 WO disclosed
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 US disclosed
US-8431730-B2 Sulfonate esters as latent acid catalysts KING INDUSTRIES (US) 2013-04-30 US disclosed
EP-2203519-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS King Industries (US) 2010-07-07 EP disclosed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 US disclosed
WO-2009045466-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2009-04-09 WO disclosed
US-4550137-A STORAGE STABLE CURABLE COATINGS PPG INDUSTRIES, INC. (US) 1985-10-29 US disclosed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4469832-A SPRAYABLE COATINGS PPG INDUSTRIES, INC. (US) 1984-09-04 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
US-4417022-A SOLVENT-FREE PPG INDUSTRIES, INC. (US) 1983-11-22 US disclosed
US-4343925-A POLYESTERS PPG INDUSTRIES, INC. (US) 1982-08-10 US disclosed
US-4317894-A Low temperature cure coating compositions PPG INDUSTRIES, INC. (US) 1982-03-02 US disclosed
US-4314918-A Coating compositions containing organic alcoholic reactive diluents PPG INDUSTRIES, INC. (US) 1982-02-09 US disclosed
US-4064087-A WITHOUT BUFFERS, FREE RADICAL CATALYSTS, ADDITION POLYMERIZATION ON PPG INDUSTRIES, INC. (US) 1977-12-20 US disclosed
US-4025407-A THERMOSETTING RESIN AND RADIATION SENSITIVE MATERIAL SUBJECTED TO IONIZING RADIATION OR ACTINIC LIGHT PPG INDUSTRIES, INC. (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA HCAR2 203/4885LMNA 306/4885AKR1B10 2945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.