SCHEMBL357565

SCHEMBL357565

O=C(/C=C/C(=O)OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.89
LMNA P02545 2/20 0.76
AKR1B10 O60218 4/20 0.69
AKR1B1 P15121 4/20 0.69
CA12 O43570 2/20 0.69
CA4 P22748 2/20 0.69
CA6 P23280 2/20 0.69
CA5A P35218 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA14 Q9ULX7 2/20 0.69
CA5B Q9Y2D0 2/20 0.69
TTR P02766 1/20 0.61
ALDH1A1 P00352 5/20 0.61
POLB P06746 1/20 0.59
TDP1 Q9NUW8 2/20 0.59
MAPK1 P28482 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337503 1.00 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL337504 1.00 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL27659194 0.98 HCAR2 (0.85) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL166653 0.94 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL527836 0.94 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL165231 0.94 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL9460386 0.94 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL9436105 0.92 HCAR2 (0.96) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL30556980 0.92 HCAR2 (0.77) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL10876347 0.92 HCAR2 (0.96) HCAR2LMNAAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 688 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114068065-B Conductive material for temperature sensor and use thereof 杭州安誉科技有限公司 2022-07-08 CN claimed
CN-113999113-B Exercise protection type lens resin monomer, preparation method and production system thereof 湖北巴乐福化工科技有限公司 2022-05-13 CN claimed
CN-113999113-A Motion protection type lens resin monomer, preparation method and production system thereof 湖北巴乐福化工科技有限公司 2022-02-01 CN claimed
CN-110637060-A Epoxy acrylate resin composition for medium refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-12-31 CN claimed
CN-110637040-A Resin composition for epoxy acrylic medium refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-12-31 CN claimed
CN-110337456-A Resin composition for epoxy acrylic refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-10-15 CN claimed
WO-2019143560-A9 METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-09-12 WO claimed
WO-2019143560-A1 METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-25 WO claimed
US-20190111016-A1 METHODS OF TREATING MUSCLE AND LIVER DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-18 US claimed
EP-3156433-B1 COATING COMPOSITIONS INCLUDING A POLYISOCYANATE CHAIN EXTENDED NH FUNCTIONAL PREPOLYMER AXALTA COATING SYSTEMS IP CO (US) 2018-06-27 EP claimed
EP-0183552-B2 A PHOTOPOLYMERIZABLE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-10-16 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US claimed
EP-0266617-A2 Modified polyphenylene ether resins having improved foamability and methods of making the same GENERAL ELECTRIC COMPANY (US) 1988-05-11 EP claimed
EP-0183552-B1 A PHOTOPOLYMERIZABLE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-03-16 EP claimed
EP-0257486-A1 Modified polyphenylene ether resins having improved processability and oxidative stability GENERAL ELECTRIC COMPANY (US) 1988-03-02 EP claimed
US-4728674-A ALPHA, BETA-UNSATURATED CARBOXYLIC ACID DERIVATIVE GENERAL ELECTRIC COMPANY (US) 1988-03-01 US claimed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP claimed
US-4684669-A LIGHTWEIGHT GENERAL ELECTRIC COMPANY (US) 1987-08-04 US claimed
EP-0183552-A2 A photopolymerizable composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-06-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190111016-A1 METHODS OF TREATING MUSCLE AND LIVER DISORDERS CKMT1A; CKMT1B, CPT1B, GLS2 HCAR2 2186/4885LMNA 511/4885AKR1B10 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.