Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COPS5 | Q92905 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Shikonin SCHEMBL33969 | 1.00 | COPS5 (1.00) | COPS5PKMEGFRMEN1MAPT | |
| Alkannin SCHEMBL29765423 | 1.00 | COPS5 (1.00) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL29418981 | 1.00 | COPS5 (1.00) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL3182028 | 1.00 | COPS5 (1.00) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL29410804 | 1.00 | COPS5 (1.00) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL28793157 | 0.99 | COPS5 (0.97) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL21616442 | 0.99 | COPS5 (0.97) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL28807982 | 0.99 | COPS5 (0.97) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL28793156 | 0.99 | COPS5 (0.97) | COPS5PKMEGFRMEN1MAPT | |
| Shikonin SCHEMBL27882249 | 0.99 | COPS5 (0.97) | COPS5PKMEGFRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8417 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228644-B1 | N-[4-[1-(1,4-DIOXASPIRO[4.5]DEC-8-YL)-4-(8-OXA-3-AZABICYCLO[3.2.1]OCT-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-YL]PHENYL]-N'-METHYLUREA FOR USE IN THE TREATMENT OF COVID19 | NANTCELL INC (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122079752-A | Preparation method of 1,4,5, 8-tetramethoxynaphthalene compound containing shikonin characteristic side chain and 6-fluoro derivative thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081221-A | Traditional Chinese medicine composite cell culture solution and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075650-A | Mongolian medicine composition for treating skin diseases caused by damp-heat toxin accumulation | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075336-A | Composition for repairing skin barrier and resisting inflammation after medical and medical non-operative treatment and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075366-A | Preparation method of low-odor arnebia euchroma (Royle) Johnst extract, and product and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| EP-3841097-B1 | 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER | BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) | 2026-05-20 | — | — | EP | claimed |
| CN-122056977-A | Hemorrhoid ointment and preparation method thereof | 安徽姥太家制药有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122063205-A | Method for rapidly identifying lithospermum erythrorhizon of pharmacopoeia and lithospermum erythrorhizon of non-pharmacopoeia by punching microsampling method | 苏州市药品检验检测研究中心（苏州市药品不良反应监测中心） | 2026-05-19 | — | — | CN | claimed |
| CN-122060429-A | Sodium-containing modified polyvinylidene fluoride binder and preparation method and application thereof | 江西量子新能源科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-0475186-A1 | Polymer scale preventive agent, and polymerization vessel and method for preventing polymer scale deposition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-03-18 | — | — | EP | claimed |
| CN-1059151-A | Polymer scale scale preventive agent and prevent the method for polymer scale deposition with it | SHINETSU CHEMICAL CO (JP) | 1992-03-04 | — | — | CN | claimed |
| EP-0467276-A2 | Polymer scale preventive agent and method of preventing polymer scale deposition using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | claimed |
| US-5073174-A | Hair, two stage, deep warm colors | L'OREAL (FR) | 1991-12-17 | — | — | US | claimed |
| CN-1037650-A | NUTRITIOUS HEALTH CREAM | WANG LAN (CN) | 1989-12-06 | — | — | CN | claimed |
| US-4751075-A | Anhydrous cosmetic compositions for thermal skin treatments | REDKEN LABORATORIES, INC. (US) | 1988-06-14 | — | — | US | claimed |
| US-4717664-A | TWO STAGE CULTURE; INCREASED PRODUCTION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-01-05 | — | — | US | claimed |
| EP-0071999-B1 | METHOD FOR PRODUCING SECONDARY METABOLITES OF PLANTS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-03-26 | — | — | EP | claimed |
| US-4560511-A | Method of producing shikonin | KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 1985-12-24 | — | — | US | claimed |
| US-4560554-A | ODORLESS-MIXTURE OF KETONE NEUTRALIZER AND OXIDIZER | SHISEIDO COMPANY LTD. (JP) | 1985-12-24 | — | — | US | claimed |