⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoguvacine SCHEMBL6214170 | 0.98 | TSHR (0.96) | — | |
| Isoguvacine SCHEMBL7958625 | 0.98 | BLM (1.00) | — | |
| Isoguvacine SCHEMBL15260680 | 0.96 | TSHR (0.92) | — | |
| SCHEMBL9568927 | 0.84 | TSHR (0.72) | — | |
| SCHEMBL29439268 | 0.80 | TSHR (0.67) | — | |
| SCHEMBL2032868 | 0.80 | — | — | |
| SCHEMBL9497437 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL14311854 | 0.78 | BLM (0.68) | — | |
| Hydrochloric Acid SCHEMBL5249049 | 0.78 | BLM (0.68) | — | |
| SCHEMBL29439332 | 0.77 | GABRR1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319110-A1 | SURFACE CALR CHEMICAL INDUCERS | ZON LEONARD (US) | 2025-10-16 | — | — | US | claimed |
| CN-120025976-A | Method for differentiating hematopoietic stem/progenitor cells into granulocytes | 苏州血霁生物科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| US-20250163379-A1 | METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS | HEMACELL BIOTECHNOLOGY INC. (CN) | 2025-05-22 | — | — | US | claimed |
| WO-2025085689-A1 | EXTRACELLULAR SMALL MOLECULE ACTIVATORS TARGETING BESTROPHIN CHANNELS FOR DISEASE TREATMENT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-04-24 | — | — | WO | claimed |
| EP-4540374-A1 | SURFACE CALR CHEMICAL INDUCERS | The Children's Medical Center Corporation (US) | 2025-04-23 | — | — | EP | claimed |
| WO-2025024501-A1 | NEUROMODULATORY PEPTIDES | LACTOCORE, INC. (US) | 2025-01-30 | — | — | WO | claimed |
| US-12201631-B2 | Methods and compositions for reducing tactile dysfunction and anxiety associated with autism spectrum disorder, Rett syndrome, and fragile X syndrome | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-01-21 | — | — | US | claimed |
| US-12161695-B2 | GABA A receptor agonists for treatment of disorders influenced by dysfunction BETA cells | DIAMYD MEDICAL AB (SE) | 2024-12-10 | — | — | US | claimed |
| US-20240390311-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING MEDICAL CONDITIONS RELATING TO CORONAVIRUS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-28 | — | — | US | claimed |
| CN-118786209-A | Method for differentiating hematopoietic stem/progenitor cells into NK cells | 苏州血霁生物科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| EP-0840601-A1 | NON-ALLOSTERIC GABA-A AGONISTS FOR TREATING SLEEP DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1998-05-13 | — | — | EP | claimed |
| EP-0789567-A1 | A METHOD FOR TREATING VASCULAR HEADACHES | THE GENERAL HOSPITAL CORPORATION (US) | 1997-08-20 | — | — | EP | claimed |
| WO-1997002813-A1 | NON-ALLOSTERIC GABAA AGONISTS FOR TREATING SLEEP DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1997-01-30 | — | — | WO | claimed |
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | claimed |
| CN-1130059-A | Use of an agonisl substances of a receptors associated with a chlorine channel in the treatment of wrinkles | OREAL (FR) | 1996-09-04 | — | — | CN | claimed |
| WO-1996015782-A1 | A METHOD FOR TREATING VASCULAR HEADACHES | THE GENERAL HOSPITAL CORPORATION (US) | 1996-05-30 | — | — | WO | claimed |
| US-5430175-A | Caged carboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-07-04 | — | — | US | claimed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | claimed |
| EP-0537993-A1 | Nicotinic activity of a series of arecolones and isoarecolones | ELI LILLY AND COMPANY (US) | 1993-04-21 | — | — | EP | claimed |
| EP-0000167-A1 | 1,2,3,6-Tetrahydroisonicotinic acid and derivatives thereof, methods and starting products for their preparation, and pharmaceutical compositions containing them. | Krogsgaard-Larsen, Povl (DK) | 1979-01-10 | — | — | EP | claimed |