Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.60 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393588 | 0.94 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3394933 | 0.94 | CSNK2A2 (0.60) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3396818 | 0.93 | CSNK2A2 (0.56) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3396383 | 0.92 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3393872 | 0.91 | CSNK2A2 (0.52) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3397310 | 0.90 | CSNK2A2 (0.56) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3397141 | 0.90 | CSNK2A2 (0.51) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3393212 | 0.90 | TNIK (0.56) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3398669 | 0.89 | CSNK2A2 (0.49) | CSNK2A2CSNK2A1NPC1RAB9ATP53 | |
| SCHEMBL3393897 | 0.87 | TNIK (0.49) | CSNK2A2CSNK2A1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | CSNK2A2 18/4885CSNK2A1 24/4885NPC1 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.