Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397155 | 0.89 | CSNK2A2 (0.60) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL3393588 | 0.84 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1NPC1KMT2ARAB9A | |
| SCHEMBL3394933 | 0.83 | CSNK2A2 (0.60) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL3396818 | 0.82 | CSNK2A2 (0.56) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL3396383 | 0.82 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL15559615 | 0.81 | TNIK (0.68) | CSNK2A2CSNK2A1TUBB8BTUBB4ATUBB | |
| SCHEMBL3393872 | 0.81 | CSNK2A2 (0.52) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL3397310 | 0.80 | CSNK2A2 (0.56) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL3397141 | 0.80 | CSNK2A2 (0.51) | CSNK2A2CSNK2A1NPC1MEN1KMT2A | |
| SCHEMBL3393212 | 0.80 | TNIK (0.56) | CSNK2A2CSNK2A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | CSNK2A2 18/4885CSNK2A1 24/4885TUBB8B 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.