Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308851 | 0.92 | HTT (0.59) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL1904597 | 0.84 | HTT (0.52) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL31275761 | 0.82 | HTT (0.50) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL8718142 | 0.80 | HTT (0.48) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL30181660 | 0.80 | HTT (0.48) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL698633 | 0.80 | HTT (0.48) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL8083410 | 0.80 | HTT (0.48) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL10262809 | 0.80 | HTT (0.48) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL695953 | 0.80 | HTT (0.48) | HTTALDH1A1FABP7CA1CA2 | |
| SCHEMBL575206 | 0.80 | ALDH1A1 (0.62) | HTTALDH1A1FABP7SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247686-A1 | HEAT TRANSFER APPARATUS AND METHODS INCLUDING HYDROFLUOROCARBONATES | 3M Innovative Properties Company (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009094278-A1 | HEAT TRANSFER APPARATUS AND METHODS INCLUDING HYDROFLUOROCARBONATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |