Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315135 | 1.00 | PTPN1 (0.34) | PTPN1PTPN6PTPN11NTMT1POLB | |
| SCHEMBL2138203 | 0.85 | ALDH1A1 (0.33) | GAA | |
| SCHEMBL2142166 | 0.85 | ALDH1A1 (0.33) | GAA | |
| SCHEMBL314951 | 0.85 | PTPN1 (0.34) | PTPN1PTPN6PTPN11POLBGAA | |
| SCHEMBL314950 | 0.85 | PTPN1 (0.34) | PTPN1PTPN6PTPN11POLBGAA | |
| SCHEMBL3399022 | 0.84 | CYP2A6 (0.37) | PTPN1NTMT1 | |
| SCHEMBL314611 | 0.84 | CYP2A6 (0.37) | PTPN1NTMT1 | |
| SCHEMBL314668 | 0.81 | BRD4 (0.32) | — | |
| SCHEMBL314667 | 0.81 | BRD4 (0.32) | — | |
| SCHEMBL314670 | 0.81 | PTPN1 (0.32) | PTPN1PTPN6PTPN11NTMT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |