Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425271 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HCRTR2POLBKMT2ADPP4 | |
| SCHEMBL3403094 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HCRTR2POLBKMT2ADPP4 | |
| SCHEMBL3425807 | 0.91 | ALDH1A1 (0.33) | ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL2686950 | 0.91 | ALDH1A1 (0.33) | ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL3399866 | 0.83 | KMT2A (0.38) | KMT2A | |
| SCHEMBL3402893 | 0.83 | KMT2A (0.38) | KMT2A | |
| SCHEMBL3402447 | 0.83 | KMT2A (0.38) | KMT2A | |
| SCHEMBL3398141 | 0.81 | KMT2A (0.32) | ALDH1A1POLBKMT2ACYP1A2 | |
| SCHEMBL3428768 | 0.81 | POLB (0.31) | POLBDPP4 | |
| SCHEMBL15808517 | 0.79 | PREP (0.36) | HCRTR2POLBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | claimed |
| EP-2247594-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | Nycomed GmbH (DE) | 2010-11-10 | — | — | EP | claimed |
| WO-2009106531-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2009-09-03 | — | — | WO | claimed |
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| EP-2247594-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | Nycomed GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009106531-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2009-09-03 | — | — | WO | disclosed |