SCHEMBL3397672

SCHEMBL3397672

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nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
MPI P34949 1/20 0.39
PDE4A P27815 1/20 0.35
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
AKR1B1 P15121 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22412510 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL285568 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL9736991 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL129544 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL8057 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL9737359 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL187554 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL9737508 1.00 LMNA (0.41) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL2387363 0.98 LMNA (0.39) LMNAL3MBTL1TDP1MPIPDE4A
SCHEMBL9736985 0.98 TDP1 (0.43) LMNAL3MBTL1TDP1MPIPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2244553-A2 GENETICALLY MODIFIED PHOTOAUTOTROPHIC ETHANOL PRODUCING HOST CELLS, METHOD FOR PRODUCING THE HOST CELLS, CONSTRUCTS FOR THE TRANSFORMATION OF THE HOST CELLS, METHOD FOR TESTING A PHOTOAUTOTROPHIC STRAIN FOR A DESIRED GROWTH PROPERTY AND METHOD OF PRODUCING ETHANOL USING THE HOST CELLS Algenol Biofuels Inc. (US) 2010-11-03 EP disclosed
WO-2009098089-A2 GENETICALLY MODIFIED PHOTOAUTOTROPHIC ETHANOL PRODUCING HOST CELLS, METHOD FOR PRODUCING THE HOST CELLS, CONSTRUCTS FOR THE TRANSFORMATION OF THE HOST CELLS, METHOD FOR TESTING A PHOTOAUTOTROPHIC STRAIN FOR A DESIRED GROWTH PROPERTY AND METHOD OF PRODUCING ETHANOL USING THE HOST CELLS BAIER KERSTIN (DE) 2009-08-13 WO disclosed