Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404019 | 0.84 | MEN1 (0.63) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL6481322 | 0.84 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL1059693 | 0.80 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL23638517 | 0.79 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2GAAMAPT | |
| SCHEMBL29087538 | 0.79 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL30037937 | 0.78 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL757031 | 0.78 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL15800270 | 0.78 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL19214776 | 0.78 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2LMNAGAA | |
| SCHEMBL30699261 | 0.78 | MAPT (0.43) | RAB9ANPC1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246334-A1 | MEDICINAL COMPOSITION FOR INHIBITING AMYLOID- PROTEIN DEPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-11-03 | — | — | EP | disclosed |