SCHEMBL339786

SCHEMBL339786

CO[Si](C(C)C)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1591560 0.70
SCHEMBL339538 0.67
Methoxymethane SCHEMBL28497941 0.61
SCHEMBL3978662 0.60
Ethyne SCHEMBL28318377 0.55
SCHEMBL9934076 0.55
Isobutane SCHEMBL7741602 0.55
SCHEMBL275873 0.51
SCHEMBL28095 0.51
SCHEMBL37611 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1183250-B1 SEMI-SYNTHESIS OF PACLITAXEL USING DIALKYLDICHLOROSILANES BRISTOL MYERS SQUIBB CO (US) 2006-10-11 EP claimed
JP-2003502290-A 2003-01-21 JP claimed
EP-1183250-A4 SEMI-SYNTHESIS OF PACLITAXEL USING DIALKYLDICHLOROSILANES BRISTOL MYERS SQUIBB CO (US) 2002-11-13 EP claimed
EP-1183250-A1 SEMI-SYNTHESIS OF PACLITAXEL USING DIALKYLDICHLOROSILANES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-03-06 EP claimed
US-6242614-B1 10-DEACETYLBACCATIN-III WHICH IS PROTECTED AT THE 7-POSITION WITH A DIALKYLALKOXYSILYL PROTECTING GROUP; ANTITUMOR AGENTS BRISTOL-MYERS SQUIBB COMPANY 2001-06-05 US claimed
WO-2000073293-A1 SEMI-SYNTHESIS OF PACLITAXEL USING DIALKYLDICHLOROSILANES BRISTOL-MYERS SQUIBB CO. (US) 2000-12-07 WO claimed
CN-110358445-B Composition for forming water-repellent film and water-repellent film 信越化学工业株式会社 2022-06-17 CN disclosed
US-11118072-B2 Water repellent film-forming composition and water repellent film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-14 US disclosed
EP-3553121-B1 WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM SHINETSU CHEMICAL CO (JP) 2021-06-09 EP disclosed
US-20190315972-A1 WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-10-17 US disclosed
EP-3553121-A1 WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM Shin-Etsu Chemical Co., Ltd. (JP) 2019-10-16 EP disclosed
EP-2065455-B1 Pressure-sensitive adhesive tape NITTO DENKO CORP (JP) 2012-05-16 EP disclosed
US-20120015100-A1 Pressure-Sensitive Adhesive Tape NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
EP-2383321-A2 Process for producing an adhesive composition and adhesive tape comprising an adhesive composition produced by said process Nitto Denko Corporation (JP) 2011-11-02 EP disclosed
US-20090142593-A1 PRESSURE-SENSITIVE ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2009-06-04 US disclosed
EP-2065455-A1 Pressure-sensitive adhesive tape NITTO DENKO CORPORATION (JP) 2009-06-03 EP disclosed
US-7030253-B2 Chemical intermediates for preparing taxane antitumor agents; forming paclitaxel derivatives by silation, esterification, carbonation, catalylic hydrogenation; protecting the 7-hydroxyl paclitaxel precursor using a strong base lithium tert-butoxide BRISTOL-MYERS SQUIBB COMPANY (US) 2006-04-18 US disclosed
US-20050282840-A1 Methods of modulating neurotrophin-mediated activity PAINCEPTOR PHARMA CORPORATION (CA) 2005-12-22 US disclosed
US-20050054863-A1 Process for preparing 4-alkyl- or 4-aryl-oxycarbonyl paclitaxel analogs and novel intermediates BRISTOL-MYERS SQUIBB COMPANY 2005-03-10 US disclosed
WO-2005016904-A1 PROCESS FOR PREPARING 4-ALKYL-OR 4-ARYL-OXYCARBONYL PACLITAXEL ANALOGS AND NOVEL INTERMEDIATES BRISTOL-MYERS SQUIBB COMPANY (US) 2005-02-24 WO disclosed