SCHEMBL1591560

SCHEMBL1591560

CC(C)[Si](O[Si](C(C)C)C(C)C)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339786 0.70
SCHEMBL3978662 0.62
SCHEMBL14940573 0.53 ALDH1A1 (0.30)
SCHEMBL2406 0.53 ALDH1A1 (0.30)
SCHEMBL41780 0.53
SCHEMBL430968 0.50
Iodide SCHEMBL20500202 0.50
Bromide SCHEMBL20500171 0.50
SCHEMBL29289367 0.50
SCHEMBL5473985 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11208430-B2 Modified oligonucleotides and methods for their synthesis NOOGEN LLC (RU) 2021-12-28 US claimed
US-10870674-B2 2020-12-22 US claimed
US-10766918-B2 2020-09-08 US claimed
US-10494388-B2 Compounds useful in the synthesis of halichondrin B analogs EISAI R&D MANAGEMENT CO., LTD. (JP) 2019-12-03 US claimed
US-20180162885-A1 COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS EISAI R&D MANAGEMENT CO., LTD. (JP) 2018-06-14 US claimed
US-9856276-B2 Compounds useful in the synthesis of halichondrin B analogs EISAI R&D MANAGEMENT CO., LTD. (JP) 2018-01-02 US claimed
US-9751909-B2 Synthesis and uses of nucleic acid compounds with conformationally restricted monomers MARINA BIOTECH, INC. (US) 2017-09-05 US claimed
US-20160376294-A1 COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS EISAI R&D MANAGEMENT CO., LTD. (JP) 2016-12-29 US claimed
US-9382262-B2 Compounds useful in the synthesis of halichondrin B analogs EISAI R&D MANAGEMENT CO., LTD. (JP) 2016-07-05 US claimed
US-20150175620-A1 COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS EISAI R&D MANAGEMENT CO., LTD. (JP) 2015-06-25 US claimed
US-20110184190-A1 COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS EISAI R&D MANAGEMENT CO., LTD. (JP) 2011-07-28 US claimed
US-20110172438-A1 Enantioselective Cascade Michael-Michael Reactions and Related Catalysts NATIONAL SCIENCE FOUNDATION 2011-07-14 US claimed
WO-2010027510-A2 ENANTIOSELECTIVE CASCADE MICHAEL-MICHAEL REACTIONS AND RELATED CATALYSTS STC. UNM (US) 2010-03-11 WO claimed
EP-2001896-A2 MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION Agilent Technologies, Inc. (US) 2008-12-17 EP claimed
US-7342003-B2 Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2008-03-11 US claimed
WO-2007112263-A2 MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION AGILENT TECHNOLOGIES, INC. (US) 2007-10-04 WO claimed
US-20070100136-A1 Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection AGILENT TECHNOLOGIES, INC. 2007-05-03 US claimed
US-20060135466-A1 Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. 2006-06-22 US claimed
WO-2005033121-A2 SYNTHESIS OF 2-ARALKYLOXYADENOSINES, 2-ALKOXYADENOSINES, AND THEIR ANALOGS KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) 2005-04-14 WO claimed
EP-0365973-B1 Process for preparing 4-0-alkyl-rhodomycins BEHRINGWERKE AG (DE) 1993-12-15 EP claimed