Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3398037

CNC(C)=[N+](C)C.[Cl-]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17822711 0.96
SCHEMBL26932633 0.84
Dimethylformamide SCHEMBL28179967 0.76 TSHR (0.43)
Hydrochloric Acid SCHEMBL8646853 0.62
SCHEMBL1004463 0.57
Hydrochloric Acid SCHEMBL4508368 0.56
Hydrochloric Acid SCHEMBL28709376 0.54
Hydrochloric Acid SCHEMBL27535417 0.54
SCHEMBL23169946 0.54
SCHEMBL790311 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3938407-A1 MICROPARTICLES BASED ON ESTER DERIVATIVES OF HYALURONAN, METHOD OF PRODUCTION, COMPOSITION COMPRISING THEREOF AND USE THEREOF Contipro A.S. (CZ) 2022-01-19 EP disclosed
WO-2020182239-A1 MICROPARTICLES BASED ON ESTER DERIVATIVES OF HYALURONAN, METHOD OF PRODUCTION, COMPOSITION COMPRISING THEREOF AND USE THEREOF CONTIPRO A.S. (CZ) 2020-09-17 WO disclosed
EP-1934227-B1 2-HETEROARYL-PYRAZOLO-[4, 3-e]-1, 2, 4-TRIAZOLO-[1,5-c]-PYRIMIDINE AS ADENOSINE A2a RECEPTOR ANTAGONISTS SCHERING CORP (US) 2011-12-21 EP disclosed
EP-2245009-A2 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 5-BIPHENYL-4-YL-2-METHYLPENTANOIC ACID DERIVATIVES Novartis AG (CH) 2010-11-03 EP disclosed
WO-2009090251-A2 NEW PROCESSES NOVARTIS AG (CH) 2009-07-23 WO disclosed
US-7465740-B2 2-heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists SCHERING CORPORATION (US) 2008-12-16 US disclosed
EP-1934227-A1 2-HETEROARYL-PYRAZOLO-[4, 3-e]-1, 2, 4-TRIAZOLO-[1,5-c]-PYRIMIDINE AS ADENOSINE A2a RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2008-06-25 EP disclosed
WO-2007035542-A1 2-HETEROARYL-PYRAZOLO-[4, 3-e]-1, 2, 4-TRIAZOLO-[1,5-c]-PYRIMIDINE AS ADENOSINE A2a RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2007-03-29 WO disclosed
US-20070066620-A1 2-Heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists MERCK SHARP & DOHME LLC 2007-03-22 US disclosed
US-7078574-B2 Method for the intrinsically safe handling of 3-chloropropyne BASF AKTIENGESELLSCHAFT (DE) 2006-07-18 US disclosed
US-6888002-B2 Transition metal complexes with diaminocarbene ligands and their use in reactions catalyzed by transition metals BAYER AKTIENGESELLSCHAFT (DE) 2005-05-03 US disclosed
US-20040147791-A1 Method for the intrinsically safe handling of 3-chloropropyne BASF AKTIEGESELLSCHAFT (DE) 2004-07-29 US disclosed
US-20030119660-A1 Novel transition metal complexes with diaminocarbene ligands and their use in reactions catalyzed by transition metals LANXESS DEUTSCHLAND GMBH (DE) 2003-06-26 US disclosed
US-6433224-B1 REACTING AN ACID WITH PHOSGENE IN PRESENCE OF CATALYST BASF AKTIENGESELLSCHAFT (DE) 2002-08-13 US disclosed
US-5241099-A PROCESS FOR THE PREPARATION OF AMINOMETHYLENE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed