Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389134 | 1.00 | MEN1 (0.38) | MEN1MAPK1KMT2APSMB5GAA | |
| SCHEMBL3375121 | 1.00 | MEN1 (0.38) | MEN1MAPK1KMT2APSMB5GAA | |
| SCHEMBL338528 | 0.77 | MEN1 (0.37) | MEN1MAPK1KMT2APSMB5GAA | |
| SCHEMBL338526 | 0.77 | MEN1 (0.37) | MEN1MAPK1KMT2APSMB5GAA | |
| SCHEMBL338527 | 0.77 | MEN1 (0.37) | MEN1MAPK1KMT2APSMB5GAA | |
| SCHEMBL3375329 | 0.72 | MEN1 (0.35) | MEN1MAPK1KMT2APSMB5BTK | |
| SCHEMBL3375124 | 0.71 | MEN1 (0.39) | MEN1MAPK1KMT2ABTKCTSK | |
| SCHEMBL3378203 | 0.68 | BTK (0.35) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL3383031 | 0.66 | GAA (0.39) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL30124181 | 0.65 | MEN1 (0.37) | MEN1MAPK1KMT2AGAABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000608-A2 | NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES | GLUESENKAMP KARL-HEINZ (DE) | 2012-01-05 | — | — | WO | disclosed |