Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400108 | 0.97 | TSHR (0.32) | — | |
| SCHEMBL7196862 | 0.94 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL3397219 | 0.94 | CNR1 (0.31) | — | |
| SCHEMBL1455223 | 0.91 | NPC1 (0.36) | SMN1; SMN2KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL3425601 | 0.88 | SMN1; SMN2 (0.30) | SMN1; SMN2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL3397237 | 0.86 | — | — | |
| SCHEMBL3400017 | 0.85 | PTAFR (0.33) | SMN1; SMN2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL22411215 | 0.85 | NPC1 (0.33) | SMN1; SMN2NPC1LMNATP53RAB9A | |
| SCHEMBL7037878 | 0.85 | NPC1 (0.33) | SMN1; SMN2NPC1LMNATP53RAB9A | |
| SCHEMBL14448390 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235071-A2 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO AND COPOLYMERS | Novolen Technology Holdings, C.V. (NL) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009054833-A2 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO AND COPOLYMERS | NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) | 2009-04-30 | — | — | WO | disclosed |