Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL15322783 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL15324005 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL15322406 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL15323716 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL3721803 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL8740332 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL326079 | 1.00 | — | — | |
| Choline SCHEMBL7069165 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL8714154 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL9543255 | 1.00 | MEN1 (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 580 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121270638-B | Method for extracting bufadienolide from bufadienolide medicinal material and application | 亳州学院 | 2026-05-15 | — | — | CN | claimed |
| CN-118948818-A | Paraquat antidote | 西南大学 | 2024-11-15 | — | — | CN | claimed |
| CN-115786918-B | Copper alkaline chemical mechanical polishing solution | 河北工业大学 | 2024-10-15 | — | — | CN | claimed |
| EP-3669190-B1 | A RELIABLE AND REPRODUCIBLE INDUSTRIALISATION PROCESS FOR THE ELIMINATION OF AIR BUBBLES IN THE PRODUCTION OF AN ENGINEERED VASCULAR TISSUE | 1LAB SA (CH) | 2023-11-01 | — | — | EP | claimed |
| CN-115786918-A | Copper alkaline chemical mechanical polishing solution | 河北工业大学 | 2023-03-14 | — | — | CN | claimed |
| CN-114711339-A | Preparation process of puffed food for improving metabolic balance of pet dog | 江苏锦华营养科技有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114469941-A | Compound amino acid injection for preventing and treating livestock diseases as well as preparation method and application thereof | 河北科星药业有限公司 | 2022-05-13 | — | — | CN | claimed |
| US-20200208117-A1 | A RELIABLE AND REPRODUCIBLE INDUSTRIALISATION PROCESS FOR THE ELIMINATION OF AIR BUBBLES IN THE PRODUCTION OF AN ENGINEERED VASCULAR TISSUE | 1LAB SA (CH) | 2020-07-02 | — | — | US | claimed |
| EP-3669190-A1 | A RELIABLE AND REPRODUCIBLE INDUSTRIALISATION PROCESS FOR THE ELIMINATION OF AIR BUBBLES IN THE PRODUCTION OF AN ENGINEERED VASCULAR TISSUE | 1Lab SA (CH) | 2020-06-24 | — | — | EP | claimed |
| CN-110028253-A | A kind of high-performance cement and preparation method thereof | 梁剑 | 2019-07-19 | — | — | CN | claimed |
| US-20060147546-A1 | Compound consisting of precipitated silica and phosphate and use thereof as nutrient intake liquid support and as anticaking agent with nutrient intake | RHODIA CHIMIE (FR) | 2006-07-06 | — | — | US | claimed |
| CN-1684757-A | Compound consisting of precipitated silica and phosphate and use thereof as nutrient intake liquid support and as anti-caking agent with nutrient intake | RHODIA CHIMIE SA (FR) | 2005-10-19 | — | — | CN | claimed |
| EP-0984772-B1 | COMPOSITION COMPRISING A LIQUID ABSORBED ON A SUPPORT BASED ON PRECIPITATE SILICA | RHODIA CHIMIE SA (FR) | 2004-08-11 | — | — | EP | claimed |
| EP-0743922-B1 | STABILIZED ORTHOSILICIC ACID COMPRISING PREPARATION AND BIOLOGICAL PREPARATION | BIO PHARMA SCIENCES BV (NL) | 1998-07-22 | — | — | EP | claimed |
| US-5635214-A | Sorbent precipitated silica particulates | RHONE-POULENC CHIMIE (FR) | 1997-06-03 | — | — | US | claimed |
| EP-0345109-B1 | ABSORBING PRECIPITATED SILICA AND COMPOSITION BASED THEREON | RHONE-POULENC CHIMIE (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0220514-B1 | COMPOSITION FOR INCREASING THE QUANTITY AND QUALITY OF FRUITS AND FLOWERS OF PLANTS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-05-02 | — | — | EP | claimed |
| EP-0172377-B1 | SUNFLOWER REGENERATION THROUGH EMBRYOGENESIS | SUNGENE TECHNOLOGIES CORPORATION (US) | 1989-01-11 | — | — | EP | claimed |
| EP-0170904-B1 | SUNFLOWER REGENERATION THROUGH ORGANOGENESIS | SUNGENE TECHNOLOGIES CORPORATION (US) | 1989-01-11 | — | — | EP | claimed |
| EP-0171593-B1 | SUNFLOWER REGENERATION THROUGH EMBRYOGENESIS AND ORGANOGENESIS | SUNGENE TECHNOLOGIES CORPORATION (US) | 1989-01-11 | — | — | EP | claimed |