Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322815 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3399237 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2322824 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3530116 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29914245 | 0.81 | ADORA1 (0.68) | ADORA2AADORA1ALDH1A1KDM4ENPC1 | |
| SCHEMBL2326019 | 0.81 | ADORA1 (0.68) | ADORA2AADORA1ALDH1A1KDM4ENPC1 | |
| SCHEMBL31009002 | 0.80 | ADORA2A (0.67) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2325695 | 0.80 | ADORA2A (0.67) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27791446 | 0.80 | ADORA2A (0.66) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23143418 | 0.78 | ADORA2A (0.65) | ADORA2AADORA1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |