Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.96 |
| ▸ | PPARG | P37231 | 5/20 | 0.81 |
| ▸ | PPARD | Q03181 | 5/20 | 0.81 |
| ▸ | PPARA | Q07869 | 5/20 | 0.81 |
| ▸ | F7 | P08709 | 5/20 | 0.81 |
| ▸ | F3 | P13726 | 5/20 | 0.81 |
| ▸ | TERT | O14746 | 3/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | BLM | P54132 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.81 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.81 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.81 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647674 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL2230814 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL1271128 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL1017653 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL23698235 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL37277 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL23698236 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL16994321 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL1647672 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 | |
| SCHEMBL1017655 | 1.00 | FASN (0.96) | FASNPPARGPPARDPPARAF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614848-B1 | Inhaler and capsule for an inhaler | BOEHRINGER INGELHEIM INT (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-10220165-B2 | Inhalator and capsule for an inhalator | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-8772298-B2 | Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140182587-A1 | INHALATOR AND CAPSULE FOR AN INHALATOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-03 | — | — | US | disclosed |
| US-20130281461-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| CN-101939316-B | Spirocyclic heterocyclic compounds, medicaments containing said compounds, their use and processes for their preparation | BOEHRINGER INGELHEIM INT | 2013-10-02 | — | — | CN | disclosed |
| US-8497369-B2 | Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-30 | — | — | US | disclosed |
| EP-2614848-A1 | Inhaler and capsule for an inhaler | Boehringer Ingelheim International GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| EP-2245026-B1 | SPIROCYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-20110046148-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2245026-A1 | SPIROCYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND METHOD FOR THEIR PRODUCTION | Boehringer Ingelheim International GmbH (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009098061-A1 | SPIROCYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046148-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | PKD1, BPHL, CYP11B2 | FASN 3454/4885PPARG 365/4885PPARD 278/4885 |
| US-20130281461-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | PKD1, BPHL, CYP11B2 | FASN 3454/4885PPARG 365/4885PPARD 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.