Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13760229 | 0.89 | CHRM3 (0.50) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL3405100 | 0.85 | CHRM3 (0.72) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL3395625 | 0.84 | CHRM3 (0.49) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL3402039 | 0.81 | CHRM3 (0.56) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4218341 | 0.80 | CHRM3 (0.67) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4215941 | 0.80 | CHRM3 (0.79) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4211535 | 0.80 | CHRM3 (0.65) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4212875 | 0.79 | CHRM3 (0.55) | CHRM3CHRM2CHRM1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL4216002 | 0.77 | CHRM3 (0.74) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1364180 | 0.77 | CHRM3 (0.50) | CHRM3CHRM2CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2249646-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100169-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |