Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968514 | 0.87 | CHRM3 (0.93) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4099839 | 0.86 | CHRM3 (0.86) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL3399242 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4095861 | 0.84 | CHRM3 (0.88) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4105534 | 0.84 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL12725271 | 0.84 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL12725342 | 0.83 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4108965 | 0.83 | CHRM3 (0.85) | CHRM3CHRM2CHRM1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL4098300 | 0.83 | CHRM3 (0.80) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4106075 | 0.83 | CHRM3 (0.85) | CHRM3CHRM2CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2249646-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | claimed |
| WO-2009100169-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | claimed |