Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315519 | 1.00 | FYN (0.35) | FYNUSP30ABL1BCRFGFR1 | |
| SCHEMBL314637 | 0.86 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL314638 | 0.86 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL315133 | 0.85 | CHRNA7 (0.33) | FYNCYP11B1CYP11B2CHRNA7 | |
| SCHEMBL5275422 | 0.85 | RXFP1 (0.44) | MTORPIK3CACHEK1CHRNA7 | |
| SCHEMBL5283290 | 0.85 | CHRNA7 (0.44) | CHRNA7KIT | |
| SCHEMBL2138931 | 0.85 | RXFP1 (0.44) | MTORPIK3CACHEK1CHRNA7 | |
| SCHEMBL315134 | 0.85 | CHRNA7 (0.33) | FYNCYP11B1CYP11B2CHRNA7 | |
| SCHEMBL2142885 | 0.85 | CHRNA7 (0.44) | CHRNA7KIT | |
| SCHEMBL314941 | 0.84 | CHRNA7 (0.35) | MTORPIK3CACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |