Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543873 | 1.00 | CA1 (0.50) | CA1CA12CA9ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL29692735 | 0.99 | CA1 (0.49) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL29543892 | 0.96 | CA1 (0.54) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL3398064 | 0.96 | CA1 (0.54) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL11215355 | 0.91 | CA1 (0.49) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL2430187 | 0.89 | CA12 (0.45) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL31046113 | 0.88 | RAB9A (0.44) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL11470385 | 0.88 | CA1 (0.50) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL29544027 | 0.88 | CA1 (0.50) | CA1CA12CA9ALDH1A1HPGD | |
| SCHEMBL29543863 | 0.87 | CA1 (0.53) | CA1CA12CA9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601764-B1 | A CLASS OF METACASPASES | VIB VZW (BE) | 2010-04-28 | — | — | EP | disclosed |
| US-20060029995-A1 | Novel class of metacaspases | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2006-02-09 | — | — | US | disclosed |
| EP-0910658-A4 | PROTEIN EXPRESSION SYSTEM | TECHNOLOGENE INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-5935824-A | FUSION PROTEIN HAVING DOMAINS COMPRISING PROTEIN OF INTEREST, HYDROPHILLIC SPACER, ENDOPROTEASE (CARBOXYPEPTIDASE) RECOGNITION SEQUENCE, AND AFFINITY DOMAIN; FOR GENETICALLY ENGINEERED PRODUCTION; PURIFICATION USING AFFINITY DOMAIN | TECHNOLOGENE, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0910658-A1 | PROTEIN EXPRESSION SYSTEM | Technologene Inc. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997028272-A9 | PROTEIN EXPRESSION SYSTEM | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997028272-A1 | PROTEIN EXPRESSION SYSTEM | TECHNOLOGENE INC. (US) | 1997-08-07 | — | — | WO | disclosed |