Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.91 |
| ▸ | HPGD | P15428 | 5/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL458273 | 1.00 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6844323 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL30718047 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28814249 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL8683263 | 0.98 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28076184 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL299753 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL12477386 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9183232 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3853 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037903-A | Formate brine-based high-density high-temperature-resistant polymer-surfactant fracturing fluid and preparation method thereof | 西南石油大学 | 2026-05-15 | — | — | CN | claimed |
| US-12599069-B2 | Cocopeat based substrate and its manufacturing method | UNC NEWTEC LLC | 2026-04-14 | — | — | US | claimed |
| EP-4083173-B1 | LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2026-02-11 | — | — | EP | claimed |
| US-12516421-B2 | Barrier chemical mechanical planarization slurries for cobalt films | VERSUM MATERIALS US, LLC (US) | 2026-01-06 | — | — | US | claimed |
| US-20250255781-A1 | PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-08-14 | — | — | US | claimed |
| WO-2025104605-A1 | A FUNGICIDAL COMBINATION, COMPOSITION, AND USE THEREOF | UPL MAURITIUS LIMITED (MU) | 2025-05-22 | — | — | WO | claimed |
| US-20250151723-A1 | FUNGICIDAL COMBINATION, COMPOSITION, AND USE THEREOF | UPL MAURITIUS LTD (MU) | 2025-05-15 | — | — | US | claimed |
| US-12296043-B2 | Liquisoft capsules | PATHEON SOFTGELS INC. (US) | 2025-05-13 | — | — | US | claimed |
| EP-4352449-B1 | PROJECTILE PAYLOAD FOR TRAINING AMMUNITION WITH MULTI-SPECTRAL OUTPUT | CYALUME TECH INC (US) | 2025-05-07 | — | — | EP | claimed |
| CN-115504881-B | Preparation method of benzyl salicylate | 天津大加化工有限公司 | 2025-03-18 | — | — | CN | claimed |
| US-5081003-A | Developer compositions for newspaper plates | HOECHST CELANESE CORPORATION (US) | 1992-01-14 | — | — | US | claimed |
| EP-0413559-A2 | Developer composition for positive working color proofing films | HOECHST CELANESE CORPORATION (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0251139-B1 | CHEMILUMINESCENT COMPOSITION, AND A REACTIVE COMPONENT SUITABLE FOR SUCH A COMPOSITION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-09-26 | — | — | EP | claimed |
| EP-0373619-A2 | Process for preparing para-hydroxybenzoic acid | KAWASAKI STEEL CORPORATION (JP) | 1990-06-20 | — | — | EP | claimed |
| WO-1990002546-A1 | PHARMACEUTICALS MICROENCAPSULATED BY VAPOR DEPOSITED POLYMERS AND METHOD | THE RONALD T. DODGE COMPANY (US) | 1990-03-22 | — | — | WO | claimed |
| US-4788221-A | INTRANASAL ADMINISTRATION, OSTEOPOROSIS, HYPERCALCEMIA | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-11-29 | — | — | US | claimed |
| US-4784803-A | Chemiluminescent composition, and a reactive component suitable for such a composition | FARMITALIA CARLO ERBA S.P.A. (IT) | 1988-11-15 | — | — | US | claimed |
| EP-0251139-A2 | Chemiluminescent composition, and a reactive component suitable for such a composition | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-01-07 | — | — | EP | claimed |
| US-4352791-A | Potassium replacement therapy | ALZA CORPORATION (US) | 1982-10-05 | — | — | US | claimed |
| US-4112221-A | HEATING A 2',3'-O-SULFINYL-8-OXYPURINE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1978-09-05 | — | — | US | claimed |