Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611110 | 0.77 | GAA (0.54) | GAAKDM2BNPC1ALDH1A1LMNA | |
| SCHEMBL14808496 | 0.73 | GAA (0.53) | GAAKDM2BALDH1A1LMNAMAPT | |
| SCHEMBL5741372 | 0.71 | ALDH1A1 (0.51) | GAAALDH1A1PREPFAPKDM4E | |
| SCHEMBL2504314 | 0.71 | ALDH1A1 (0.51) | GAAALDH1A1PREPFAPKDM4E | |
| SCHEMBL31279942 | 0.71 | GAA (0.60) | GAAKDM2BALDH1A1LMNAMAPT | |
| SCHEMBL11762859 | 0.71 | GAA (0.60) | GAAKDM2BALDH1A1LMNAMAPT | |
| SCHEMBL8712217 | 0.70 | GAA (0.63) | GAAKDM2BNPC1ALDH1A1LMNA | |
| SCHEMBL29875548 | 0.70 | GAA (0.63) | GAAKDM2BNPC1ALDH1A1LMNA | |
| SCHEMBL26265725 | 0.69 | MEN1 (0.54) | GAAALDH1A1LMNAPREPFAP | |
| SCHEMBL17913852 | 0.69 | KDM2B (1.00) | GAAKDM2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206704-A1 | Pharmaceutically active diazepanes | Novartis AG (CH) | 2010-07-14 | — | — | EP | claimed |