SCHEMBL3399719

SCHEMBL3399719

OC[C@H](O)CNc1c2ccccc2nc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.60
RAD52 P43351 4/20 0.60
KDM4E B2RXH2 2/20 0.60
RAB9A P51151 2/20 0.60
MITF O75030 1/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
TTR P02766 1/20 0.60
GLA P06280 1/20 0.60
GAA P10253 1/20 0.60
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
SCN9A Q15858 2/20 0.48
SLC2A1 P11166 2/20 0.47
NPC1 O15118 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
KDM1A O60341 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3399725 1.00 POLB (0.60) POLBRAD52KDM4ERAB9AMITF
SCHEMBL9588712 0.83 SLC2A1 (0.42) POLBRAD52KDM4ERAB9AMITF
Hydrochloric Acid SCHEMBL10734760 0.78 EGFR (0.40) POLBRAD52KDM4ERAB9AMITF
SCHEMBL9589910 0.76 CYP2C19 (0.64)
SCHEMBL3427605 0.76 EGFR (0.43) ALDH1A1SCN9ASLC2A1
SCHEMBL3427601 0.76 EGFR (0.43) ALDH1A1SCN9ASLC2A1
SCHEMBL17154415 0.75 POLB (1.00) POLBRAD52KDM4ERAB9AMITF
Hydrochloric Acid SCHEMBL6534162 0.74 SLC2A1 (0.61) SLC2A1
SCHEMBL4325278 0.74 POLB (0.49) POLBRAD52KDM4ERAB9AMITF
Hydrochloric Acid SCHEMBL6534160 0.74 SLC2A1 (0.61) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100129800-A1 POLYMERS AND THEIR USE AS FLUORESCENT LABELS AYMAMI BOFARULL JUAN 2010-05-27 US disclosed
WO-2009007397-A1 NEW POLYMERS AND THEIR USE AS FLUORESCENT LABELS CRYSTAX PHARMACEUTICALS, S.L. (ES) 2009-01-15 WO disclosed
EP-2014698-A1 Polymers and their use as fluorescent labels Crystax Pharmaceuticals S.L. (ES) 2009-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129800-A1 POLYMERS AND THEIR USE AS FLUORESCENT LABELS CBR3, H1-0, H1-3 POLB 1028/4885RAD52 410/4885KDM4E 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.