SCHEMBL3427601

SCHEMBL3427601

Cn1c2c3ccccc3nc-2c(NC[C@H](O)CO)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.43
SRC P12931 1/20 0.43
SCN9A Q15858 2/20 0.41
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SLC2A1 P11166 1/20 0.39
TERT O14746 1/20 0.39
HSD17B10 Q99714 1/20 0.38
DNM1 Q05193 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3427605 1.00 EGFR (0.43) EGFRSRCSCN9AALDH1A1HPGD
SCHEMBL3399719 0.76 POLB (0.60) SCN9AALDH1A1SLC2A1
SCHEMBL3399725 0.76 POLB (0.60) SCN9AALDH1A1SLC2A1
SCHEMBL3290733 0.76 POLB (0.51) ALDH1A1SLC2A1TERT
SCHEMBL3298450 0.71 KAT2B (0.44) ALDH1A1SLC2A1TERTDNM1
SCHEMBL3519650 0.70 CACNA2D1 (0.40) SLC2A1
SCHEMBL9588712 0.70 SLC2A1 (0.42) EGFRSCN9AALDH1A1SLC2A1
Biscryptolepine SCHEMBL30192568 0.70 TERT (0.54) ALDH1A1HPGDSMN1; SMN2TERTHSD17B10
SCHEMBL5811815 0.70 TERT (0.40) ALDH1A1HPGDSMN1; SMN2TERT
SCHEMBL3292083 0.70 RAD52 (0.47) SLC2A1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100129800-A1 POLYMERS AND THEIR USE AS FLUORESCENT LABELS AYMAMI BOFARULL JUAN 2010-05-27 US disclosed
EP-2014698-A1 Polymers and their use as fluorescent labels Crystax Pharmaceuticals S.L. (ES) 2009-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129800-A1 POLYMERS AND THEIR USE AS FLUORESCENT LABELS CBR3, H1-0, H1-3 EGFR 1939/4885SRC 3966/4885SCN9A 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.