Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663703 | 1.00 | GAA (0.59) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL14154101 | 1.00 | GAA (0.59) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL93071 | 1.00 | GAA (0.59) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL16736608 | 0.90 | GAA (0.58) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL16736849 | 0.90 | TSHR (0.57) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL487428 | 0.86 | GAA (0.67) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL339877 | 0.83 | GAA (0.63) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL683547 | 0.83 | HSD17B10 (0.69) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL3152462 | 0.82 | GAA (0.62) | GAAALDH1A1USP2PKMHPGD | |
| SCHEMBL9336626 | 0.82 | TSHR (0.72) | GAAALDH1A1USP2PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301908-B1 | (-)-stereoisomer of 2,6-di-sec-butylphenol and analogs thereof for promoting antiemetic effect, treatment of nausea and vomiting and treatment of migraine | SIGNATURE THERAPEUTICS INC (US) | 2014-06-25 | — | — | EP | disclosed |
| EP-2146946-B1 | (-)- stereoisomer of 2,6-di-sec-butylphenol and analogs thereof | PHARMACOFORE INC (US) | 2010-11-10 | — | — | EP | disclosed |