Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 6/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315927 | 1.00 | FFAR2 (0.35) | FFAR2BRD4CREBBPBRD2KMT2A | |
| SCHEMBL2413089 | 0.87 | FFAR2 (0.38) | FFAR2BRD4CREBBPBRD2KMT2A | |
| SCHEMBL2413091 | 0.87 | FFAR2 (0.38) | FFAR2BRD4CREBBPBRD2KMT2A | |
| SCHEMBL314667 | 0.85 | BRD4 (0.32) | FFAR2BRD4 | |
| SCHEMBL314668 | 0.85 | BRD4 (0.32) | FFAR2BRD4 | |
| SCHEMBL1973110 | 0.83 | GRIN1 (0.36) | — | |
| SCHEMBL1973109 | 0.83 | GRIN1 (0.36) | — | |
| SCHEMBL3398578 | 0.82 | GPBAR1 (0.36) | FFAR2BRD4BRD2ALDH1A1 | |
| SCHEMBL314817 | 0.82 | GPBAR1 (0.36) | FFAR2BRD4BRD2ALDH1A1 | |
| SCHEMBL316757 | 0.82 | KDM4E (0.32) | KMT2AKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |