SCHEMBL3400178

SCHEMBL3400178

Clc1ccccc1-c1cccc(NCc2cc(-c3ccccc3)[nH]n2)n1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 13/20 0.45
CYP1A2 P05177 5/20 0.44
CYP3A4 P08684 5/20 0.44
CYP2D6 P10635 4/20 0.44
CYP2C19 P33261 4/20 0.44
TSHR P16473 3/20 0.44
CLK4 Q9HAZ1 3/20 0.44
MAPK1 P28482 2/20 0.44
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 2/20 0.42
GBA1 P04062 1/20 0.42
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13426106 0.87 FYN (0.46) CCNT1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13426334 0.86 RAB9A (0.49) CCNT1ALDH1A1
SCHEMBL3392166 0.86 CYP1A2 (0.44) CCNT1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13426139 0.83 CYP1A2 (0.47) CCNT1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13426333 0.83 CYP1A2 (0.47) CCNT1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13425542 0.83 CLK4 (0.41) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
SCHEMBL13425685 0.82 MAPT (0.41) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
SCHEMBL13425514 0.80 FFAR1 (0.43) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
SCHEMBL13425533 0.79 KCNH2 (0.45) CCNT1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13425520 0.74 KCNH2 (0.41) CCNT1CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed