Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194624 | 1.00 | HTR1A (0.64) | HTR1AKDM4EALDH1A1HTTTP53 | |
| SCHEMBL1194558 | 0.84 | KDM4E (0.56) | HTR1AKDM4EALDH1A1HTTTP53 | |
| SCHEMBL16447735 | 0.78 | HTR1A (1.00) | HTR1AKDM4EALDH1A1HTTTDP1 | |
| SCHEMBL16447736 | 0.78 | HTR1A (1.00) | HTR1AKDM4EALDH1A1HTTTDP1 | |
| SCHEMBL1195286 | 0.78 | ATM (0.61) | KDM4EALDH1A1HTTTP53ALOX15 | |
| SCHEMBL1195907 | 0.78 | HTR1A (0.61) | HTR1AKDM4EALDH1A1HTTTDP1 | |
| SCHEMBL21595803 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1HTTTP53ALOX15 | |
| SCHEMBL15346331 | 0.77 | HTR1A (0.67) | HTR1AKDM4EALDH1A1HTTTDP1 | |
| SCHEMBL8295970 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1HTTTP53ALOX15 | |
| SCHEMBL1194800 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HTTTP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247571-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | Uniwersytet Jagiellonski (PL) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009093916-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2009-07-30 | — | — | WO | disclosed |