Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Adenosine Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.90 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.90 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.90 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.90 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.90 |
| ▸ | SRC | P12931 | 2/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.90 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.90 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.90 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.90 |
| ▸ | LDHA | P00338 | 1/20 | 0.90 |
| ▸ | FBP1 | P09467 | 1/20 | 0.90 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.90 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.90 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.90 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.90 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.90 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.90 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.90 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Phosphate SCHEMBL1448053 | 0.99 | P2RY1 (0.92) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL1829884 | 0.99 | P2RY1 (0.92) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL30298370 | 0.99 | P2RY1 (0.92) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL27762258 | 0.98 | P2RY1 (0.90) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL1338615 | 0.95 | P2RY1 (1.00) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL132458 | 0.95 | P2RY1 (1.00) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL13170051 | 0.95 | P2RY1 (1.00) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL19420134 | 0.95 | P2RY1 (1.00) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL11977309 | 0.95 | P2RY1 (1.00) | P2RY1P2RY2TAS1R3TAS1R1SRC | |
| Adenosine Phosphate SCHEMBL13374692 | 0.95 | P2RY1 (1.00) | P2RY1P2RY2TAS1R3TAS1R1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046149-B1 | ENRICHED INFANT FORMULAS | ABBOTT LAB (US) | 2010-11-03 | — | — | EP | disclosed |