Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400639 | 0.81 | MME (0.46) | BTK | |
| SCHEMBL15906230 | 0.80 | EPHX1 (0.50) | — | |
| SCHEMBL14748226 | 0.79 | EPHX1 (0.54) | — | |
| SCHEMBL24312848 | 0.76 | EPHX1 (0.57) | SMYD3 | |
| SCHEMBL14652117 | 0.76 | KDM5A (0.38) | SMYD3BTK | |
| SCHEMBL21984724 | 0.75 | EPHX1 (0.48) | — | |
| SCHEMBL20748429 | 0.73 | EPHX1 (0.52) | — | |
| SCHEMBL20748435 | 0.73 | EPHX1 (0.52) | — | |
| SCHEMBL9003889 | 0.73 | EPHX2 (0.61) | SMYD3 | |
| SCHEMBL1412068 | 0.73 | EPHX2 (0.61) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | claimed |
| EP-2247594-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | Nycomed GmbH (DE) | 2010-11-10 | — | — | EP | claimed |
| WO-2009106531-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2009-09-03 | — | — | WO | claimed |
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| EP-2247594-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | Nycomed GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009106531-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2009-09-03 | — | — | WO | disclosed |