Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279710 | 0.94 | EPHX2 (0.32) | MEN1GAAKMT2A | |
| SCHEMBL397513 | 0.94 | EPHX2 (0.32) | MEN1GAAKMT2A | |
| SCHEMBL397512 | 0.94 | EPHX2 (0.32) | MEN1GAAKMT2A | |
| SCHEMBL3406214 | 0.89 | CYP2D6 (0.31) | — | |
| SCHEMBL396281 | 0.87 | LMNA (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL397367 | 0.87 | LMNA (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL396280 | 0.87 | LMNA (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL3406210 | 0.83 | — | — | |
| SCHEMBL3032557 | 0.82 | FFAR4 (0.41) | TSHR | |
| SCHEMBL3400681 | 0.80 | FOLH1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250158-A2 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | Nicox S.A. (FR) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106470-A2 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | NICOX S.A. (FR) | 2009-09-03 | — | — | WO | disclosed |