Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396352 | 0.94 | MAPT (0.34) | MAPTCRHBPCRHR2L3MBTL1FAAH | |
| SCHEMBL15135361 | 0.94 | MAPT (0.34) | MAPTCRHBPCRHR2L3MBTL1FAAH | |
| SCHEMBL15135362 | 0.83 | PTGS2 (0.35) | MAPTCRHBPCRHR2L3MBTL1FAAH | |
| SCHEMBL396354 | 0.83 | PTGS2 (0.35) | MAPTCRHBPCRHR2L3MBTL1FAAH | |
| SCHEMBL396353 | 0.83 | PTGS2 (0.35) | MAPTCRHBPCRHR2L3MBTL1FAAH | |
| SCHEMBL3404736 | 0.82 | MAPT (0.30) | MAPTCRHBPCRHR2FAAHPTGS1 | |
| SCHEMBL13000821 | 0.82 | MAPT (0.30) | MAPTCRHBPCRHR2FAAHPTGS1 | |
| SCHEMBL3400688 | 0.82 | MAPT (0.30) | MAPTCRHBPCRHR2PTGS1PTGS2 | |
| SCHEMBL13001173 | 0.82 | MAPT (0.30) | MAPTCRHBPCRHR2FAAHPTGS1 | |
| SCHEMBL13000862 | 0.82 | MAPT (0.30) | MAPTCRHBPCRHR2FAAHPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250158-A2 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | Nicox S.A. (FR) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106470-A2 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | NICOX S.A. (FR) | 2009-09-03 | — | — | WO | disclosed |