Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.50 |
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402115 | 0.81 | HRH3 (0.48) | HRH3METKCNH2 | |
| SCHEMBL10293592 | 0.75 | HRH3 (0.62) | HRH3METKCNH2 | |
| SCHEMBL10293596 | 0.75 | HRH3 (0.62) | HRH3METKCNH2 | |
| SCHEMBL5217166 | 0.73 | HRH3 (0.72) | HRH3KCNH2 | |
| SCHEMBL17570419 | 0.72 | HRH3 (0.59) | HRH3METKCNH2 | |
| SCHEMBL12615622 | 0.72 | HRH3 (0.66) | HRH3 | |
| SCHEMBL12615280 | 0.72 | HRH3 (0.66) | HRH3 | |
| SCHEMBL2743633 | 0.71 | HRH3 (0.56) | HRH3METKCNH2 | |
| SCHEMBL2743632 | 0.71 | HRH3 (0.56) | HRH3METKCNH2 | |
| SCHEMBL2743650 | 0.71 | HRH3 (0.57) | HRH3METKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |