Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 7/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405573 | 0.84 | HTR2C (0.52) | CNR1CES2HTR2CPARP1SIGLEC9 | |
| SCHEMBL13309912 | 0.83 | HTR2C (0.59) | CNR1CES2HTR2CPARP1SIGLEC9 | |
| SCHEMBL13071982 | 0.82 | HTR2C (0.56) | CNR1CES2HTR2CPARP1SIGLEC9 | |
| SCHEMBL3400778 | 0.81 | HTR2C (0.57) | CNR1CES2HTR2CPARP1SIGLEC9 | |
| SCHEMBL3401781 | 0.81 | CNR1 (0.70) | CNR1HTR2CPARP1ALDH1A1HPGD | |
| SCHEMBL3401932 | 0.80 | KDM4E (0.55) | CNR1CES2HTR2CKDM4EALDH1A1 | |
| SCHEMBL3405399 | 0.78 | CNR1 (0.57) | CNR1HTR2CPARP1KDM4EALDH1A1 | |
| SCHEMBL3405384 | 0.78 | HTR2C (0.62) | CNR1CES2HTR2CPARP1HRH3 | |
| SCHEMBL3400118 | 0.78 | HTR2C (0.50) | CNR1CES2HTR2CPARP1SIGLEC9 | |
| SCHEMBL3405916 | 0.78 | CNR1 (0.51) | CNR1HTR2CPARP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |