Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404035 | 0.88 | HTR2C (0.50) | HTR2CCNR1PARP1CES2SIGLEC9 | |
| SCHEMBL3405446 | 0.88 | CNR1 (0.47) | HTR2CCNR1PARP1HRH3MEN1 | |
| SCHEMBL3400778 | 0.87 | HTR2C (0.57) | HTR2CCNR1PARP1CES2BCHE | |
| SCHEMBL13309912 | 0.87 | HTR2C (0.59) | HTR2CCNR1PARP1CES2SIGLEC9 | |
| SCHEMBL3402656 | 0.86 | HTR2C (0.48) | HTR2CCNR1PARP1HRH3MEN1 | |
| SCHEMBL3401781 | 0.84 | CNR1 (0.70) | HTR2CCNR1PARP1HRH3MEN1 | |
| SCHEMBL3401181 | 0.84 | CNR1 (0.47) | HTR2CCNR1PARP1CES2SIGLEC9 | |
| SCHEMBL3399805 | 0.83 | CNR1 (0.56) | HTR2CCNR1PARP1HRH3ALDH1A1 | |
| SCHEMBL3405399 | 0.82 | CNR1 (0.57) | HTR2CCNR1PARP1HRH3ALDH1A1 | |
| SCHEMBL3405384 | 0.82 | HTR2C (0.62) | HTR2CCNR1PARP1CES2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758976-B2 | Positive photosensitive polyimide composition | LG CHEM LTD. (KR) | 2014-06-24 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |