SCHEMBL3401541

SCHEMBL3401541

CC(N=Nc1cccc[n+]1C)=NN=c1ccccn1C

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
NPC1 O15118 1/20 0.57
PABPC1 P11940 1/20 0.57
APOBEC3A P31941 1/20 0.57
RAB9A P51151 1/20 0.57
APOBEC3G Q9HC16 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483710 1.00 KDM4E (0.57) KDM4ENPC1PABPC1APOBEC3ARAB9A
Hydrochloric Acid SCHEMBL29565890 0.99 KDM4E (0.56) KDM4ENPC1PABPC1APOBEC3ARAB9A
Hydrochloric Acid SCHEMBL1151667 0.99 KDM4E (0.56) KDM4ENPC1PABPC1APOBEC3ARAB9A
Hydrochloric Acid SCHEMBL1151664 0.99 KDM4E (0.56) KDM4ENPC1PABPC1APOBEC3ARAB9A
SCHEMBL839455 0.84 KDM4E (0.42) KDM4ENPC1PABPC1APOBEC3ARAB9A
SCHEMBL5197506 0.84 KDM4E (0.53) KDM4ENPC1PABPC1APOBEC3ARAB9A
SCHEMBL5195813 0.84 KDM4E (0.53) KDM4ENPC1PABPC1APOBEC3ARAB9A
SCHEMBL5198678 0.84 KDM4E (0.53) KDM4ENPC1PABPC1APOBEC3ARAB9A
Hydrochloric Acid SCHEMBL4798212 0.83 KDM4E (0.52) KDM4ENPC1PABPC1APOBEC3ARAB9A
Hydrochloric Acid SCHEMBL4807029 0.83 KDM4E (0.52) KDM4ENPC1PABPC1APOBEC3ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1548006-B1 Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis OREAL (FR) 2007-09-05 EP claimed
EP-1548006-A1 Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis L'OREAL (FR) 2005-06-29 EP claimed
EP-1378544-A2 Tetraaza-pentamethine derivatives and their application for dyeing keratinous fibres L'OREAL (FR) 2004-01-07 EP claimed
EP-3474814-B1 A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT AND ITS USE FOR DYEING KERATIN FIBERS OREAL (FR) 2020-11-11 EP disclosed
EP-2248515-B1 Use for dying keratinic fibers of a azomethine-type compound having a pyrazolopyridine group ORÉAL L (FR) 2015-12-23 EP disclosed
EP-2246038-B1 Azomethinic cationic pyrazolidine derivatives for dyeing keratin fiber ORÉAL L (FR) 2014-10-22 EP disclosed
EP-2248515-A1 Use for dying keratinic fibers of a azomethine-type compound having a pyrazolopyridine group L'Oréal (FR) 2010-11-10 EP disclosed
EP-2246038-A1 Azomethinic cationic pyrazolidine derivatives for dyeing keratin fiber L'Oréal (FR) 2010-11-03 EP disclosed
EP-2011787-A1 Dying composition comprising an azomethin-type compound with a pyrazolinone moiety L'Oreal (FR) 2009-01-07 EP disclosed
EP-1980558-A1 Polycationic monochromophoric compounds of hydrazone type, dyeing compositions comprising same and dyeing method L'Oréal (FR) 2008-10-15 EP disclosed
WO-2007122340-A1 CATIONIC DICHROMOPHORIC COMPOUND CONTAINING TWO UNITS OF HYDRAZONE TYPE AND COMPRISING A CATIONIC LINKER ARM, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, METHOD FOR THE USE THEREOF AND USES L'ORÉAL (FR) 2007-11-01 WO disclosed
EP-1548006-B1 Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis OREAL (FR) 2007-09-05 EP disclosed
EP-1548006-A1 Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis L'OREAL (FR) 2005-06-29 EP disclosed
EP-1378544-A2 Tetraaza-pentamethine derivatives and their application for dyeing keratinous fibres L'OREAL (FR) 2004-01-07 EP disclosed