Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483865 | 0.87 | CA1 (0.32) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| SCHEMBL839121 | 0.87 | CA1 (0.32) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| Hydrochloric Acid SCHEMBL5228745 | 0.87 | CA1 (0.32) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| Hydrochloric Acid SCHEMBL1152259 | 0.86 | CA1 (0.31) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| Hydrochloric Acid SCHEMBL1152262 | 0.86 | CA1 (0.31) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| SCHEMBL21927056 | 0.85 | KDM4E (0.32) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| SCHEMBL3401541 | 0.84 | KDM4E (0.57) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| SCHEMBL483710 | 0.84 | KDM4E (0.57) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| Hydrochloric Acid SCHEMBL1151664 | 0.83 | KDM4E (0.56) | KDM4ENPC1PABPC1APOBEC3ARAB9A | |
| Hydrochloric Acid SCHEMBL29565890 | 0.83 | KDM4E (0.56) | KDM4ENPC1PABPC1APOBEC3ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544576-B1 | DYE COMPOSITION COMPRISING 12-HYDROXYSTEARIC ACID, AN ORGANIC AMINE AND A DYE | OREAL (FR) | 2021-08-18 | — | — | EP | disclosed |
| WO-2021130088-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | L'OREAL (FR) | 2021-07-01 | — | — | WO | disclosed |
| WO-2018096132-A1 | DYE COMPOSITION COMPRISING 12-HYDROXYSTEARIC ACID, AN ORGANIC AMINE AND A DYE | L'OREAL (FR) | 2018-05-31 | — | — | WO | disclosed |
| EP-2333018-B1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'ORÉAL (FR) | 2017-11-22 | — | — | EP | disclosed |
| EP-2198843-B1 | Lightening of human keratinic fibers with a anhydrous composition comprising a mixture of monoethanolamine/basic amine acid and kit | L'ORÉAL (FR) | 2017-09-13 | — | — | EP | disclosed |
| EP-2198833-B1 | Method of coloring or lightening of human keratinic fibers with an anhydrous composition and an inorganic base and kit | L'ORÉAL (FR) | 2017-07-26 | — | — | EP | disclosed |
| WO-2017109182-A1 | COMPOSITION COMPRISING AT LEAST TWO DIFFERENT STARCHES AND A COLOURING AGENT | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| EP-2198924-B1 | METHOD FOR DYEING KERATIN MATERIALS IN THE PRESENCE OF AN EMULSION COMPRISING A DYE AND AN ALKALINE AGENT, AND AN OXIDISING COMPOSITION | L'ORÉAL (FR) | 2017-05-24 | — | — | EP | disclosed |
| EP-2198831-B1 | Method for lightening, lightening direct dyeing or oxidation dyeing carried out in the presence of an organic amine and a mineral base; suitable kit | L'ORÉAL (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2338571-B1 | Agent for colouring and/or bleaching keratinous fibres in two parts, including a particular fatty body and a reductone | L'ORÉAL (FR) | 2017-05-10 | — | — | EP | disclosed |
| US-7288122-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| US-7288639-B2 | Dyssymmetrical diazo compounds having at least one 4-pyridinium unit and a cationic or non-cationic linker, compositions comprising them, method of coloring, and device | L'OREAL S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| US-7288124-B2 | Heteroaromatic binuclear black direct dyes | L'OREAL S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| US-7285138-B2 | Cationic diazo compound, compositions comprising at least one cationic diazo compound as a direct dye, a process for dyeing keratin fibers and device therefore | L'OREAL, S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7282069-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-10-16 | — | — | US | disclosed |
| WO-2007110530-A2 | SPECIFIC DYES OF NAPHTHALIMIDE TYPE, DYEING COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USES | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |
| US-7247713-B2 | Symmetrical diazo compounds containing 2-pyridinium groups and cationic or non-cationic linker, compositions comprising them, method of coloring, and device | L'OREAL, S.A. (FR) | 2007-07-24 | — | — | US | disclosed |
| US-7208586-B2 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2007-04-24 | — | — | US | disclosed |
| US-20070044250-A1 | Cationic azo dyes with julolidine units, dyeing composition containing them, method of dyeing | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| US-20070010663-A1 | Dissymmetrical diazo compounds containing having at least one 2-imidazolium unit and a cationic or non-cationic linker, compositions comprising them, method of coloring, and device | L'OREAL S.A. (FR) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044250-A1 | Cationic azo dyes with julolidine units, dyeing composition containing them, method of dyeing | KRT18, IK, ACR | KDM4E 545/4885NPC1 4542/4885PABPC1 2323/4885 |
| US-20070010663-A1 | Dissymmetrical diazo compounds containing having at least one 2-imidazolium unit and a cationic or non-cationic linker, compositions comprising them, method of coloring, and device | KRT18, DSP, DSG1 | KDM4E 1240/4885NPC1 4662/4885PABPC1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.