Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25477021 | 0.81 | LMNA (0.46) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL13434931 | 0.79 | LMNA (0.55) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL30421227 | 0.79 | LMNA (0.44) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL21565937 | 0.75 | LMNA (0.50) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL43187 | 0.73 | — | — | |
| SCHEMBL14611823 | 0.72 | LMNA (0.52) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL10795986 | 0.72 | LMNA (0.52) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL23355753 | 0.71 | LMNA (0.38) | LMNACA12CA1CA9CA2 | |
| SCHEMBL42299 | 0.70 | — | — | |
| SCHEMBL17830449 | 0.70 | LMNA (0.44) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268446-B1 | METHOD FOR PRODUCING ASYMMETRICAL 4,6-BIS(ARYLOXY)PYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-10-06 | — | — | EP | claimed |