Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | AGXT | P21549 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 11/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362259 | 0.95 | IDO1 (0.53) | IDO1AGXTMAOBTAAR1ALDH1A1 | |
| SCHEMBL29830809 | 0.78 | IDO1 (0.64) | IDO1AGXTMAOBTAAR1ALDH1A1 | |
| SCHEMBL514760 | 0.78 | IDO1 (0.64) | IDO1AGXTMAOBTAAR1ALDH1A1 | |
| SCHEMBL1767187 | 0.77 | IDO1 (0.69) | IDO1AGXTMAOBTAAR1MAOA | |
| SCHEMBL10623645 | 0.77 | MAOB (0.47) | IDO1AGXTMAOBALDH1A1MAOA | |
| SCHEMBL106501 | 0.74 | TSHR (0.52) | IDO1AGXTMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL11019421 | 0.74 | IDO1 (0.60) | IDO1AGXTMAOBTAAR1ALDH1A1 | |
| SCHEMBL30487709 | 0.74 | IDO1 (0.60) | IDO1AGXTMAOBTAAR1ALDH1A1 | |
| SCHEMBL8132483 | 0.74 | IDO1 (0.60) | IDO1AGXTMAOBTAAR1ALDH1A1 | |
| SCHEMBL9347048 | 0.74 | IDO1 (0.64) | IDO1AGXTMAOBTAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2249647-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100168-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |