SCHEMBL30487709

SCHEMBL30487709

CCOCc1cccc(Br)c1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.60
AGXT P21549 2/20 0.60
MAOB P27338 10/20 0.56
TAAR1 Q96RJ0 3/20 0.47
MAOA P21397 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45
PARP15 Q460N3 1/20 0.44
PARP14 Q460N5 1/20 0.44
PARP10 Q53GL7 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8132483 1.00 IDO1 (0.60) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL1767187 0.87 IDO1 (0.69) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL649159 0.85 TSHR (0.46) IDO1AGXT
SCHEMBL6624646 0.85 IDO1 (0.56) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL9347048 0.83 IDO1 (0.64) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL6291712 0.82 IDO1 (0.62) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL22469745 0.82 TSHR (0.62) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL31568444 0.82 TSHR (0.62) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL17241276 0.81 IDO1 (0.49) IDO1AGXTMAOBTAAR1MAOA
SCHEMBL9628682 0.81 TSHR (0.48) IDO1AGXTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110799490-B 3-arylpropionamide compound and method for producing 3-arylpropionate compound 住友化学株式会社 2023-05-02 CN disclosed