Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403346 | 0.89 | MLYCD (0.36) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3406275 | 0.89 | MLYCD (0.36) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3409564 | 0.88 | MLYCD (0.35) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3403843 | 0.86 | PDE3B (0.35) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3409022 | 0.86 | MLYCD (0.35) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3403239 | 0.85 | MLYCD (0.35) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3405824 | 0.85 | MLYCD (0.34) | MLYCDPDE3BPDE3AP2RY12 | |
| SCHEMBL3409373 | 0.84 | EPHX2 (0.35) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3407491 | 0.84 | PDE3B (0.35) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3407428 | 0.84 | MLYCD (0.34) | MLYCDL3MBTL1PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |