⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698539 | 0.79 | — | — | |
| SCHEMBL17023613 | 0.75 | — | — | |
| SCHEMBL8313074 | 0.75 | — | — | |
| SCHEMBL125358 | 0.72 | — | — | |
| SCHEMBL15067739 | 0.72 | TRPA1 (0.31) | — | |
| SCHEMBL3733647 | 0.69 | KDM4E (0.38) | — | |
| SCHEMBL8065611 | 0.69 | — | — | |
| SCHEMBL11863 | 0.68 | — | — | |
| SCHEMBL1969746 | 0.68 | — | — | |
| SCHEMBL2137791 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889672-B2 | Compounds, formulations, and methods of protein kinase C inhibition | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-11-18 | — | — | US | claimed |
| US-20120302561-A1 | Compounds, Formulations, and Methods of Protein Kinase C Inhibition | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | US | claimed |
| WO-2012149452-A1 | COMPOUNDS, FORMULATIONS, AND METHODS OF PROTEIN KINASE C INHIBITION | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-01 | — | — | WO | claimed |
| US-8012652-B2 | Method of forming a thin film pattern and method of fabricating a liquid crystal display device | LG DISPLAY CO., LTD. (KR) | 2011-09-06 | — | — | US | claimed |
| US-20080264902-A1 | Method of forming a thin film pattern and method of fabricating a liquid crystal display device | LG ELECTRONICS INC. (KR) | 2008-10-30 | — | — | US | claimed |
| US-20080173615-A1 | Etch resist solution, method of fabricating thin film pattern using the same and method of fabricating an LCD device using the same | LG DISPLAY CO., LTD. (KR) | 2008-07-24 | — | — | US | claimed |
| EP-1441724-B8 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | SERONO LAB (CH) | 2007-10-17 | — | — | EP | claimed |
| EP-1441724-B1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS (AN) | 2007-09-05 | — | — | EP | claimed |
| EP-1363873-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | claimed |
| JP-2005504093-A | — | — | 2005-02-10 | — | — | JP | claimed |
| US-20040198799-A1 | Methods of increasing endogenous testosterone levels | LABORATOIRES SERONO SA (CH) | 2004-10-07 | — | — | US | claimed |
| EP-1441724-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | Applied Research Systems ARS Holding S.A. (AN) | 2004-08-04 | — | — | EP | claimed |
| EP-1363873-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2003026649-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-04-03 | — | — | WO | claimed |
| WO-2002070541-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | claimed |
| US-4433057-A | Chemical reagent indicator for the in vitro diagnosis of pregnancy | SOCIETY ANSTALT SAID (LI) | 1984-02-21 | — | — | US | claimed |
| JP-56125858-A | — | — | None | — | — | JP | disclosed |
| US-8889672-B2 | Compounds, formulations, and methods of protein kinase C inhibition | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-11-18 | — | — | US | disclosed |
| US-4166044-A | REACTIVE DYES, WATER AND ALCOHOL SOLVENTS, ABRASION RESISTANT, MOISTURE RESISTANT | AMERICAN CAN COMPANY (US) | 1979-08-28 | — | — | US | disclosed |
| US-4155895-A | ADHESION, RESOLES, INDICATOR DYES | AMERICAN CAN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |