Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.59 |
| ▸ | GIPR | P48546 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719587 | 0.80 | GCGR (0.69) | GCGRGIPRKCNH2 | |
| SCHEMBL3403361 | 0.75 | GCGR (0.48) | GCGRGIPRKCNH2PPARGPPARD | |
| SCHEMBL2642977 | 0.75 | GCGR (0.80) | GCGRGIPRKCNH2 | |
| SCHEMBL2642979 | 0.75 | GCGR (0.80) | GCGRGIPRKCNH2 | |
| SCHEMBL2662074 | 0.74 | GCGR (1.00) | GCGRGIPRKCNH2 | |
| SCHEMBL926279 | 0.74 | GCGR (1.00) | GCGRGIPRKCNH2 | |
| SCHEMBL928245 | 0.74 | GCGR (1.00) | GCGRGIPRKCNH2 | |
| SCHEMBL2642763 | 0.74 | GCGR (1.00) | GCGRGIPRKCNH2 | |
| SCHEMBL2644443 | 0.74 | GCGR (1.00) | GCGRGIPRKCNH2 | |
| SCHEMBL2642764 | 0.74 | GCGR (1.00) | GCGRGIPRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |