Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.48 |
| ▸ | GIPR | P48546 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719164 | 0.81 | GCGR (0.55) | GCGRGIPRKCNH2MAPTMAT2A | |
| SCHEMBL3403430 | 0.75 | GCGR (0.59) | GCGRGIPRKCNH2MAPTPPARG | |
| SCHEMBL3402377 | 0.72 | PHGDH (0.46) | — | |
| SCHEMBL721555 | 0.72 | GCGR (0.55) | GCGRGIPRKCNH2MAPT | |
| SCHEMBL719587 | 0.72 | GCGR (0.69) | GCGRGIPRKCNH2 | |
| SCHEMBL721420 | 0.70 | GCGR (0.60) | GCGRGIPRKCNH2 | |
| SCHEMBL722052 | 0.69 | GCGR (0.48) | GCGRGIPRKCNH2 | |
| SCHEMBL719157 | 0.68 | GCGR (0.51) | GCGRGIPRKCNH2MAPT | |
| SCHEMBL2643230 | 0.68 | GCGR (0.55) | GCGRGIPRKCNH2MAPTPPARG | |
| SCHEMBL2643736 | 0.66 | GCGR (0.51) | GCGRGIPRKCNH2MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |