SCHEMBL3403502

SCHEMBL3403502

CCCCCCCCNC(=O)NCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.69
EPHX1 P07099 9/20 0.65
ALDH1A1 P00352 1/20 0.65
HTT P42858 1/20 0.65
KEAP1 Q14145 1/20 0.59
NFE2L2 Q16236 1/20 0.59
NAAA Q02083 1/20 0.59
HPGD P15428 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11035774 1.00 EPHX2 (0.69) EPHX2EPHX1ALDH1A1HTTKEAP1
SCHEMBL11260446 1.00 EPHX2 (0.69) EPHX2EPHX1ALDH1A1HTTKEAP1
SCHEMBL3420583 1.00 EPHX2 (0.69) EPHX2EPHX1ALDH1A1HTTKEAP1
SCHEMBL4985255 0.98 EPHX2 (0.71) EPHX2EPHX1ALDH1A1HTTKEAP1
SCHEMBL3421197 0.93 EPHX2 (0.73) EPHX2EPHX1ALDH1A1HTTKEAP1
SCHEMBL11034979 0.92 EPHX1 (0.68) EPHX2EPHX1ALDH1A1HTT
SCHEMBL11035964 0.92 EPHX1 (0.68) EPHX2EPHX1ALDH1A1HTT
SCHEMBL6436358 0.92 EPHX2 (0.80) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2
SCHEMBL6438376 0.92 EPHX2 (0.80) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2
SCHEMBL6436792 0.92 EPHX2 (0.80) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2254126-A1 Organogel for electrical cable insulating layer Nexans (FR) 2010-11-24 EP disclosed
EP-2254127-A1 Organogel for electrical cable insulating layer Nexans (FR) 2010-11-24 EP disclosed
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed
EP-1042761-A1 AN INSULATED ELECTRIC DIRECT CURRENT CABLE ABB AB (SE) 2000-10-11 EP disclosed
WO-1999033068-A1 AN INSULATED ELECTRIC DIRECT CURRENT CABLE ABB AB (SE) 1999-07-01 WO disclosed