SCHEMBL6436792

SCHEMBL6436792

O=C(NCCCCCCNC(=O)NCc1ccccc1)NCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.80
EPHX1 P07099 2/20 0.73
KEAP1 Q14145 2/20 0.68
NFE2L2 Q16236 2/20 0.68
FES P07332 1/20 0.66
RET P07949 1/20 0.66
MARK3 P27448 1/20 0.66
TYK2 P29597 1/20 0.66
FLT4 P35916 1/20 0.66
SYK P43405 1/20 0.66
CLK2 P49760 1/20 0.66
CLK4 Q9HAZ1 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.62
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA4 P22748 1/20 0.57
CA5A P35218 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6438376 1.00 EPHX2 (0.80) EPHX2EPHX1KEAP1NFE2L2FES
SCHEMBL6436358 1.00 EPHX2 (0.80) EPHX2EPHX1KEAP1NFE2L2FES
SCHEMBL6435482 0.94 EPHX2 (0.83) EPHX2EPHX1KEAP1NFE2L2FES
SCHEMBL12914915 0.93 EPHX2 (0.71) EPHX2EPHX1KEAP1NFE2L2FES
SCHEMBL11035774 0.92 EPHX2 (0.69) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2
SCHEMBL15741794 0.92 EPHX2 (0.69) EPHX2EPHX1KEAP1NFE2L2FES
SCHEMBL3420583 0.92 EPHX2 (0.69) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2
SCHEMBL12553499 0.92 EPHX2 (0.69) EPHX2EPHX1KEAP1NFE2L2FES
SCHEMBL3403502 0.92 EPHX2 (0.69) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2
SCHEMBL11260446 0.92 EPHX2 (0.69) EPHX2EPHX1KEAP1NFE2L2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed
US-4888321-A SUBBING AND RECORDING LAYERS EACH CONTAINING HEAT FUSIBLE MATERIAL WITH DEFINED MELTING POINT FUJI PHOTO FILM CO., LTD. (JP) 1989-12-19 US disclosed
US-4533929-A ANIONIC SURFACTANTS AS ANTIFOGGING AGENTS; DIETHYLHEXYL SULFOSUCCINATE FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US disclosed
US-4520377-A COLOR FORMING LAYER COMO/SED OF ELECTRON DONATING COLORLESS DYE, ELECTRON ACCEPTING COMPOUND, NAPHTHOL UREA AND/OR URETHANE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1985-05-28 US disclosed
US-4401717-A CONTAINING A CHROMOGEN, A PHENOL LAND A UREA OR CARBAMATE; THERMOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-08-30 US disclosed