Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279837 | 0.87 | OPRK1 (0.35) | OPRK1GAA | |
| SCHEMBL3279842 | 0.87 | OPRK1 (0.35) | OPRK1GAA | |
| SCHEMBL3279840 | 0.87 | OPRK1 (0.35) | OPRK1GAA | |
| SCHEMBL21196260 | 0.86 | OPRK1 (0.31) | OPRK1 | |
| SCHEMBL16054309 | 0.86 | OPRK1 (0.31) | OPRK1 | |
| SCHEMBL16054312 | 0.86 | OPRK1 (0.31) | OPRK1 | |
| SCHEMBL17028497 | 0.84 | OPRK1 (0.32) | OPRK1GAA | |
| SCHEMBL3025369 | 0.80 | CYP46A1 (0.34) | GAANPC1RAB9AALDH1A1 | |
| SCHEMBL1314601 | 0.80 | CYP46A1 (0.34) | GAANPC1RAB9AALDH1A1 | |
| SCHEMBL3025364 | 0.80 | CYP46A1 (0.34) | GAANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252613-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM, LLC (BM) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009105717-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-08-27 | — | — | WO | disclosed |